Name of the responsible structure
- Philippe Lesnik, Anatol Kontush
Guardianship of the structure
- ICAN, INSERM
Referent person for trade with MetaboHUB
- Farid Ichou, Marie Lhomme
Location
- Pitié-Salpêtrière Hospital, 75013, Paris
Website
Domain
Health, Clinical and Preclinical Research
Services
Non-targeted approach
Profiling method
Targeted approach
Analytical capacity with the kind of mastered technical
Analytical capacity ~ 4000-5000 Echts / year
Number of samples 2015: 2300 Echts
Number of samples 2016: + 4200 Echts
Techniques mastered
(Liquid Injections, Headspace, SPME), Liq-Liq Extraction, SPE, Dosage Proteine precellys (tissue homogenization), LC-HRMS, LC-MS / MS, LC-MSn,
Equipments
UPLC (Acquity) - Q-Exactive (ThermoFisher)
HPLC (Shimadzu) -QTrap 4000 (AB / Sciex)
GC-MS ISQ (ThermoFisher)
Skills and Human Resources
Staff - 5 people:
Philippe Lesnik - DR INSERM / UPMC: expertise in integrative biology of atherosclerosis and more particularly interaction immune system and microbiota
Anatol Kontush - DR INSERM / UPMC: expertise in metabolism of lipoproteins and lipids and atherosclerosis
Marie Lhomme - IR ICAN: expertise in development and realization of lipidomic analysis by MS in biological fluids (plasma-serum, urine), tissue (adipose, liver, brain), feces, cells and bacteria. Structural elucidation of lipids by MS / MS
Farid Ichou - IR ICAN: expertise in development and realization of metabolomic analyzes by MS in biological fluids (plasma-serum, CSF, urine), tissue (adipose, liver, brain), feces, cells, structural elucidation by MS / MS And development of an approach to identification assistance, measurement of metabolites derived from the microbiota
Florent Japiot - Tech ICAN: expertise in the realization of lipidomic and metabolomic analyzes
Quality approach
Application for ISO9001 accreditation for 2017